For Automated Extraction of Circulating-Free Genomic DNA from Plasma, Serum, and Body Fluids

MagCore® Plasma DNA Extraction Kit can be used to isolate cell-free DNA with high sensitivity for cancer diagnosis, detection of genetic disorder in prenatal testing and more. Our patented magnetic beads will bind to the short DNA fragments with high affinity. This highly specific binding technology will ensure that all important genetic information is collected efficiently.

Product
Code 105 MagCore® Plasma DNA Extraction Kit (1.2ml)
Code 115 MagCore® Circulating DNA Large Volume Kit (4ml)
Features
  1. Consistent and reproducible results.
  2. Cartridges are pre-filled and sealed to prevent contamination
  3. Minimal manual pipetting, complete automatic procedure from cell lysis to elution
Applications

MagCore® automated extraction systems allow processing multiple sample types in the same run, including:

  1. Plasma
  2. Serum
  3. Body fluids

Purified DNA available for direct usage in downstream applications, such as:

  1. PCR and real-time quantitative PCR
  2. Southern Blot
  3. Next Generation Sequencing
  4. Genotyping
Performance
  • Plasma Table-1

    Table 1. Comparison of cfDNA yield extracted from MagCore® and other competitors. cfDNA concentration measured with Qubit dsDNA HS Assay Kit.
  • Plasma-1

    Figure 1. Gel electrophoresis of cell-free DNA extracted from human plasma and human serum samples. The integrity and quantity of purified cell-free DNA was analyzed using Agilent Bioanalyzer 2100. Ladder: Agilent High Sensitivity DNA Kit Ladder; Plasma: Cell-free DNA of 150-200bp was extracted; Serum: cell-free DNA of around 200bp, 350bp, and 550bp were extracted.
  • Plasma-2

    Figure 2. Gel electrophoresis of Cell-free DNA extracted from human plasma samples analyzed by Agilent Bioanalyzer 2100. Cell-free DNA was extracted from plasma samples of 5 healthy individuals. Cell-free DNA of 150-200bp was extracted.
Specifications
MagCore® Plus II/Super/HF16 Plus
Cartridge Code96 PrepsRunning Time
Cat No.
105MPD120074 mins (sample volume: 1200µl)
MagCore® HF48
Cartridge Code96 PrepsRunning TimeRunning Time
Cat No.
105MPD120066 mins (sample volume: 1200µl)135 mins (sample volume: 1200µl)
Components Available for Purchase
ProductCat No.Content
Proteinase K SetPK01111 mg Proteinase K, 1.25 ml PK Storage Buffer
RNase ARN05050µl RNase A (50mg/ml)
RN130130µl RNase A (51mg/ml)