For Automated Extraction of Genomic DNA from Forensic Samples
MagCore® Forensic DNA Direct Kit is designed to extract total DNA from forensic samples such as dried blood spot, swab samples, cigarette butts, hair roots, seminal stain and chorionic villus for prenatal testing. The unique design of our FS tips and program allow users to load forensic samples directly onto MagCore® automated extraction systems without any pretreatment. Our patented magnetic beads will bind to DNA fragments with high affinity. This highly specific binding technology will ensure that all important genetic information is collected efficiently.
Product
Code 406 MagCore® Forensic DNA Direct Kit
Features
- Unique FS Tip design: Hermetic seal to minimize aerosol contamination and Porous holder to filter out solid debris
- Consistent and reproducible results
- Cartridges are pre-filled and sealed to prevent contamination
- Minimal manual pipetting, complete automatic procedure directly from sample to elution
Applications
MagCore® automated extraction systems allow processing multiple sample types in the same run, including:
- Dried blood spot
- Swab samples: Dried blood, Saliva, Body fluids
- Cigarette butts
- Hair roots
- Seminal stain
- Chorionic villus
Purified DNA available for direct usage in downstream applications, such as:
- PCR and real-time quantitative PCR
- Southern Blot
- Next Generation Sequencing
- Genotyping
Unique Pipette Tip Design
Novel Patented FS Tip
- Hermetic Seal: Airtight assurance
- Minimal aerosol contamination
- Automatic separation of solid debris
Performance
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Figure 1A. Results of direct DNA extraction from dried blood samples. Guthrie card spotted with 30, 15, 7.5, and 2 µl of dried blood from an healthy individual were applied to MagCore® automated extraction program 406C.
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Figure 1B. Results of direct DNA extraction from dried blood samples. Fabric spotted with 30, 15, 7.5, and 2 µl of dried blood from an healthy individual were applied to MagCore® automated extraction program 406C.
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Figure 2. Results of direct DNA extraction from seminal stain samples. Fabric spotted with 30, 15, 7.5, and 2 µl of semen from an healthy individual were applied to MagCore® automated extraction program 406C.
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Figure 3A. Results of direct DNA extraction from dried saliva samples. Guthrie card spotted with 30, 15, 7.5, and 2 µl of dried saliva were applied to MagCore® automated extraction program 406A.
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Figure 3B. Results of direct DNA extraction from dried saliva samples. Fabric spotted with 30, 15, 7.5, and 2 µl of dried saliva were applied to MagCore® automated extraction program 406A.
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Figure 4. Results of direct DNA extraction from various sample sources. Samples of specified sizes: Buccal cell on swab, Cigarette butt, Chewing gum, Hair root, Nail were applied to MagCore® automated extraction. Suitable program for each sample type is indicated in the program selection guide.
Program Selection Guide
Specifications
| MagCore® Plus II/Super/HF16 Plus | ||
|---|---|---|
| Cartridge Code | 72 Preps | Running Time |
| Cat No. | ||
| 406 | MFC-03 | 125 mins |
| Components Available for Purchase | ||
|---|---|---|
| Product | Cat No. | Content |
| Proteinase K Set | PK011 | 11 mg Proteinase K, 1.25 ml PK Storage Buffer |
| RNase A | RN050 | 50µl RNase A (50mg/ml) |
| RN130 | 130µl RNase A (51mg/ml) | |